October 11, 2022 2 min read

Super-agers have Super-sized Neurons

Superagers have long been a mystery to scientists. Despite being in their 80s they have the physical ability and cognitive function similar to someone in middle age.

Now, researchers at Northwestern University in Illinois may have discovered one of the reasons superagers are able to stay so mentally sharp: the neurons in their entorhinal cortex, a part of the brain responsible for storing memories, is much larger than those of their cognitively average peers.

Furthermore, these neurons showed no sign of tau tangles – abnormal accumulations of protein that collect inside neurons and limit the communication between them that are a tell-tale sign of Alzheimer’s disease.


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